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-Structure paper
Title | Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1. |
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Journal, issue, pages | Nat. Chem. Biol., Vol. 5, Page 758-764, Year 2009 |
Publish date | Jun 9, 2009 (structure data deposition date) |
![]() | Hindie, V. / Stroba, A. / Zhang, H. / Lopez-Garcia, L.A. / Idrissova, L. / Zeuzem, S. / Hirschberg, D. / Schaeffer, F. / Jrgensen, T.J. / Engel, M. ...Hindie, V. / Stroba, A. / Zhang, H. / Lopez-Garcia, L.A. / Idrissova, L. / Zeuzem, S. / Hirschberg, D. / Schaeffer, F. / Jrgensen, T.J. / Engel, M. / Alzari, P.M. / Biondi, R.M. |
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Methods | X-ray diffraction |
Resolution | 1.9 - 1.91 Å |
Structure data | ![]() PDB-3hrc: ![]() PDB-3hrf: |
Chemicals | ![]() ChemComp-ATP: ![]() ChemComp-HOH: ![]() ChemComp-P47: ![]() ChemComp-EPE: |
Source |
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![]() | TRANSFERASE / AGC Kinase / PHOSPHORYLATION / ALLOSTERY / PDK1 / ACTIVATION LOOP / ATP BINDING / ATP-binding / Kinase / Membrane / Nucleotide-binding / Phosphoprotein / Serine/threonine-protein kinase / PIF-POCKET / ALPHA-C HELIX |