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TitleHigh affinity interaction of the p53 peptide-analogue with human Mdm2 and Mdmx.
Journal, issue, pagesCell Cycle, Vol. 8, Page 1176-1184, Year 2009
Publish dateNov 26, 2008 (structure data deposition date)
AuthorsCzarna, A. / Popowicz, G.M. / Pecak, A. / Wolf, S. / Dubin, G. / Holak, T.A.
External linksCell Cycle / PubMed:19305137
MethodsX-ray diffraction
Resolution1.4 - 1.8 Å
Structure data

PDB-3fdo:
Structure of human MDMX in complex with high affinity peptide
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

PDB-3g03:
Structure of human MDM2 in complex with high affinity peptide
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCELL CYCLE / MDMX / MDM4 / MDM-X / MDM-4 / p53 / MDM2 / Hdm2 / Hdmx / cancer / apoptosis / Alternative splicing / Cytoplasm / Host-virus interaction / Ligase / Metal-binding / Nucleus / Phosphoprotein / Proto-oncogene / Ubl conjugation / Ubl conjugation pathway / Zinc / Zinc-finger

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