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Structure paper

TitleStructure of Staphylococcus aureus 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
Journal, issue, pagesActa Crystallogr. ,Sect. F, Vol. 64, Page 343-350, Year 2008
Publish dateDec 10, 2007 (structure data deposition date)
AuthorsSiu, K.K. / Lee, J.E. / Smith, G.D. / Horvatin-Mrakovcic, C. / Howell, P.L.
External linksActa Crystallogr. ,Sect. F / PubMed:18453700
MethodsX-ray diffraction
Resolution1.7 - 1.95 Å
Structure data

PDB-3bl6:
Crystal structure of Staphylococcus aureus 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase in complex with formycin A
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-3df9:
Crystal structure of E. coli MTA/SAH nucleosidase in complex with BnT-DADMeImmA
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-FMC:
(1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol

ChemComp-HOH:
WATER

ChemComp-DF9:
(3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(benzylsulfanyl)methyl]pyrrolidin-3-ol

Source
  • staphylococcus aureus (bacteria)
  • escherichia coli (E. coli)
KeywordsHYDROLASE / nucleosidase / MTAN / alpha and beta proteins / mixed alpha/beta dimer

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