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Structure paper

TitleStructural effects of nucleobase variations at key active site residue Ade38 in the hairpin ribozyme.
Journal, issue, pagesRna, Vol. 14, Page 1600-1616, Year 2008
Publish dateOct 25, 2007 (structure data deposition date)
AuthorsMacElrevey, C. / Salter, J.D. / Krucinska, J. / Wedekind, J.E.
External linksRna / PubMed:18596253
MethodsX-ray diffraction
Resolution2.25 - 2.75 Å
Structure data

PDB-3b58:
Minimally Junctioned Hairpin Ribozyme Incorporates A38G Mutation and a 2',5'-Phosphodiester Linkage at the Active Site
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

PDB-3b5a:
Crystal Structure of a Minimally Hinged Hairpin Ribozyme Incorporating A38G mutation with a 2'OMe modification at the active site
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

PDB-3b5f:
Crystal Structure of a Minimally Hinged Hairpin Ribozyme Incorporating the Ade38Dap Mutation and a 2',5' Phosphodiester Linkage at the Active Site
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-3b5s:
Minimally Hinged Hairpin Ribozyme Incorporates A38DAP Mutation and 2'-O-methyl Modification at the Active Site
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-3b91:
Minimally Hinged Hairpin Ribozyme Incorporates Ade38(2AP) and 2',5'-Phosphodiester Linkage Mutations at the Active Site
Method: X-RAY DIFFRACTION / Resolution: 2.75 Å

PDB-3bbi:
Minimally Junctioned Hairpin Ribozyme Incorporating A38(2AP) and A-1 2'-O-Me Modifications near Active Site
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

PDB-3bbk:
Miminally Junctioned Hairpin Ribozyme Incorporates A38C and 2'5'-phosphodiester Linkage within Active Site
Method: X-RAY DIFFRACTION / Resolution: 2.75 Å

PDB-3bbm:
Minimally Junctioned Hairpin Ribozyme Incorporates A38C and 2'O-Me Modification at Active Site
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

PDB-3cr1:
crystal structure of a minimal, mutant, all-RNA hairpin ribozyme (A38C, A-1OMA) grown from MgCl2
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-NCO:
COBALT HEXAMMINE(III)

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

KeywordsRNA / hairpin ribozyme; 2' / 5' phosphodiester / hairpin ribozyme / 2'O-methyl / ribozyme / hairpin ribozyme; 2 / 6 diaminopurine; RNA; 2' / 5' phosphodiester linkage / hairpin ribozyme; RNA; 2 / 6 diaminopurine; 2'-O-methyl / hairpin ribozyme; 2'5' phosphodiester; RNA; 2-aminopurine / 2-aminopurine / phosphoryl transfer / linker / A38C / 2'5'-phosphodiester / reverse linkage / small ribozyme / A38

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