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Structure paper

TitleTARP auxiliary subunits switch AMPA receptor antagonists into partial agonists.
Journal, issue, pagesScience, Vol. 318, Page 815-817, Year 2007
Publish dateOct 30, 2007 (structure data deposition date)
AuthorsMenuz, K. / Stroud, R.M. / Nicoll, R.A. / Hays, F.A.
External linksScience / PubMed:17975069
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-3b7d:
Crystal structure of the GLUR2 ligand binding core (HS1S2J) in complex with CNQX at 2.5 A resolution
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-CNI:
7-nitro-2,3-dioxo-2,3-dihydroquinoxaline-6-carbonitrile

ChemComp-HOH:
WATER

Source
  • rattus norvegicus (Norway rat)
KeywordsMEMBRANE PROTEIN / S1S2 / CNQX / Structural Genomics / PSI-2 / Protein Structure Initiative / Center for Structures of Membrane Proteins / CSMP / Cell junction / Glycoprotein / Ion transport / Ionic channel / Lipoprotein / Palmitate / Phosphorylation / Postsynaptic cell membrane / Receptor / RNA editing / Synapse / Transmembrane / Transport

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