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-Structure paper
Title | Structural basis for compound C inhibition of the human AMP-activated protein kinase alpha 2 subunit kinase domain |
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Journal, issue, pages | Acta Crystallogr. ,Sect. D, Vol. 67, Page 480-487, Year 2011 |
Publish date | May 4, 2007 (structure data deposition date) |
Authors | Handa, N. / Takagi, T. / Saijo, S. / Kishishita, S. / Takaya, D. / Toyama, M. / Terada, T. / Shirouzu, M. / Suzuki, A. / Lee, S. ...Handa, N. / Takagi, T. / Saijo, S. / Kishishita, S. / Takaya, D. / Toyama, M. / Terada, T. / Shirouzu, M. / Suzuki, A. / Lee, S. / Yamauchi, T. / Okada-Iwabu, M. / Iwabu, M. / Kadowaki, T. / Minokoshi, Y. / Yokoyama, S. |
External links | Acta Crystallogr. ,Sect. D / PubMed:21543851 |
Methods | X-ray diffraction |
Resolution | 2.08 - 3.02 Å |
Structure data | PDB-2yza: PDB-3aqv: |
Chemicals | ChemComp-HOH: ChemComp-TAK: |
Source |
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Keywords | TRANSFERASE / Signaling protein / Serine/threonine protein kinase / Phosphorylation / ATP-binding / Nucleotide-binding / Cholesterol biosynthesis / Fatty acid biosynthesis / Lipid synthesis / glucose metabolism / Magnesium / Metal-binding / Serine/threonine-protein kinase / Steroid biosynthesis / Structural Genomics / NPPSFA / National Project on Protein Structural and Functional Analyses / RIKEN Structural Genomics/Proteomics Initiative / RSGI / TRANSFERASE/TRANSFERASE INHIBITOR / TRANSFERASE-TRANSFERASE INHIBITOR complex |