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Structure paper

TitleStructure and Mechanism of the Lipooligosaccharide Sialyltransferase from Neisseria Meningitidis
Journal, issue, pagesJ. Biol. Chem., Vol. 286, Page 37237-, Year 2011
Publish dateMay 25, 2011 (structure data deposition date)
AuthorsLin, L.Y.C. / Rakic, B. / Chiu, C.P.C. / Lameignere, E. / Wakarchuk, W.W. / Withers, S.G. / Strynadka, N.C.J.
External linksJ. Biol. Chem. / PubMed:21880735
MethodsX-ray diffraction
Resolution1.94 - 2.83 Å
Structure data

PDB-2yk4:
Structure of Neisseria LOS-specific sialyltransferase (NST).
Method: X-RAY DIFFRACTION / Resolution: 1.94 Å

PDB-2yk5:
Structure of Neisseria LOS-specific sialyltransferase (NST), in complex with CMP.
Method: X-RAY DIFFRACTION / Resolution: 2.32 Å

PDB-2yk6:
Structure of Neisseria LOS-specific sialyltransferase (NST), in complex with CDP.
Method: X-RAY DIFFRACTION / Resolution: 2.83 Å

PDB-2yk7:
Structure of Neisseria LOS-specific sialyltransferase (NST), in complex with CMP-3F-Neu5Ac.
Method: X-RAY DIFFRACTION / Resolution: 2.18 Å

Chemicals

ChemComp-EGC:
2-(2-{2-[2-(2-{2-[2-(2-{2-[4-(1,1,3,3-TETRAMETHYL-BUTYL)-PHENOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOX / detergent*YM

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-C:
CYTIDINE-5'-MONOPHOSPHATE

ChemComp-PO4:
PHOSPHATE ION

ChemComp-1PE:
PENTAETHYLENE GLYCOL / precipitant*YM

ChemComp-CDP:
CYTIDINE-5'-DIPHOSPHATE

ChemComp-CSF:
CYTIDINE-5'-MONOPHOSPHATE-3-FLUORO-N-ACETYL-NEURAMINIC ACID

Source
  • neisseria meningitidis serogroup b (bacteria)
KeywordsTRANSFERASE / LIPOOLIGOSACCHARIDE SIALYLTRANSFERASE

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