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-Structure paper
Title | Structural Basis of Quinolone Inhibition of Type Iia Topoisomerases and Target-Mediated Resistance |
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Journal, issue, pages | Nat. Struct. Mol. Biol., Vol. 17, Page 1152-, Year 2010 |
Publish date | Jul 8, 2010 (structure data deposition date) |
![]() | Wohlkonig, A. / Chan, P.F. / Fosberry, A.P. / Homes, P. / Huang, J. / Kranz, M. / Leydon, V.R. / Miles, T.J. / Pearson, N.D. / Perera, R.L. ...Wohlkonig, A. / Chan, P.F. / Fosberry, A.P. / Homes, P. / Huang, J. / Kranz, M. / Leydon, V.R. / Miles, T.J. / Pearson, N.D. / Perera, R.L. / Shillings, A.J. / Gwynn, M.N. / Bax, B.D. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.2 - 3.25 Å |
Structure data | ![]() PDB-2xkj: ![]() PDB-2xkk: |
Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-GOL: ![]() ChemComp-HOH: ![]() ChemComp-MG: ![]() ChemComp-MFX: |
Source |
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![]() | ISOMERASE / TYPE IIA TOPOISOMERASE / ISOMERASE/DNA/ANTIBIOTIC / ISOMERASE-DNA-ANTIBIOTIC COMPLEX / QUINOLONE / ANTIBACTERIAL AGENT |