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-Structure paper
Title | Molecular Basis of Engineered Meganuclease Targeting of the Endogenous Human Rag1 Locus |
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Journal, issue, pages | Nucleic Acids Res., Vol. 39, Page 729-743, Year 2011 |
Publish date | May 10, 2010 (structure data deposition date) |
Authors | Munoz, I.G. / Prieto, J. / Subramanian, S. / Coloma, J. / Redondo, P. / Villate, M. / Merino, N. / Marenchino, M. / D'Abramo, M. / Gervasio, F.L. ...Munoz, I.G. / Prieto, J. / Subramanian, S. / Coloma, J. / Redondo, P. / Villate, M. / Merino, N. / Marenchino, M. / D'Abramo, M. / Gervasio, F.L. / Grizot, S. / Daboussi, F. / Smith, J. / Chion-Sotine, I. / Paques, F. / Duchateau, P. / Alibes, A. / Stricher, F. / Serrano, L. / Blanco, F.J. / Montoya, G. |
External links | Nucleic Acids Res. / PubMed:20846960 |
Methods | X-ray diffraction |
Resolution | 2.3 - 2.6 Å |
Structure data | PDB-2xe0: PDB-3mx9: PDB-3mxa: PDB-3mxb: |
Chemicals | ChemComp-ACT: ChemComp-PGO: ChemComp-MG: ChemComp-HOH: ChemComp-CA: ChemComp-MN: ChemComp-EOH: ChemComp-1PE: ChemComp-PO4: |
Source |
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Keywords | DNA BINDING PROTEIN/DNA / DNA BINDING PROTEIN-DNA COMPLEX / HOMING ENDONUCLEASES / DOUBLE-STRAND BREAK / HOMOLOGOUS RECOMBINATION / HUMAN RAG1 GENE / SEVERE COMBINED IMMUNODEFICIENCY (SCID) / DNA BINDING PROTEIN / HYDROLASE/DNA / PROTEIN-DNA COMPLEX / HYDROLASE-DNA complex |