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TitleThe Inhibition of Neisseria Meningitidis Sialic Acid Synthase by a Tetrahedral Intermediate Analog.
Journal, issue, pagesBiochemistry, Vol. 48, Page 9194-, Year 2009
Publish dateAug 25, 2009 (structure data deposition date)
AuthorsLiu, F. / Lee, H.J. / Strynadka, N.C.J. / Tanner, M.E.
External linksBiochemistry / PubMed:19719325
MethodsX-ray diffraction
Resolution1.75 Å
Structure data

PDB-2wqp:
Crystal structure of sialic acid synthase NeuB-inhibitor complex
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

Chemicals

ChemComp-WQP:
5-(ACETYLAMINO)-3,5-DIDEOXY-2-O-PHOSPHONO-D-ERYTHRO-L-MANNO-NONONIC ACID

ChemComp-MN:
Unknown entry

ChemComp-ACT:
ACETATE ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-LMR:
(2S)-2-hydroxybutanedioic acid

ChemComp-HOH:
WATER

Source
  • neisseria meningitidis (bacteria)
KeywordsTRANSFERASE / NEUB / INHIBITOR / TIM BARREL / SIALIC ACID SYNTHASE

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