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-Structure paper
Title | The Glutamate Receptor Glur5 Agonist (S)-2-Amino-3-(3-Hydroxy-7,8-Dihydro-6H-Cyclohepta[D]Isoxazol-4-Yl)Propionic Acid and the 8-Methyl Analogue: Synthesis, Molecular Pharmacology, and Biostructural Characterization |
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Journal, issue, pages | J. Med. Chem., Vol. 52, Page 4911-, Year 2009 |
Publish date | Jun 18, 2009 (structure data deposition date) |
![]() | Clausen, R.P. / Naur, P. / Kristensen, A.S. / Greenwood, J.R. / Strange, M. / Brauner-Osborne, H. / Jensen, A.A. / Nielsen, A.S. / Geneser, U. / Ringgaard, L.M. ...Clausen, R.P. / Naur, P. / Kristensen, A.S. / Greenwood, J.R. / Strange, M. / Brauner-Osborne, H. / Jensen, A.A. / Nielsen, A.S. / Geneser, U. / Ringgaard, L.M. / Nielsen, B. / Pickering, D.S. / Brehm, L. / Gajhede, M. / Krogsgaard-Larsen, P. / Kastrup, J.S. |
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Methods | X-ray diffraction |
Resolution | 2.2 Å |
Structure data | ![]() PDB-2wky: |
Chemicals | ![]() ChemComp-CL: ![]() ChemComp-IBC: ![]() ChemComp-HOH: |
Source |
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![]() | MEMBRANE PROTEIN / SYNAPSE / MEMBRANE / RECEPTOR / TRANSPORT / ION CHANNEL / RNA EDITING / GLYCOPROTEIN / CELL JUNCTION / IONOTROPIC GLUTAMATE RECEPTOR / ALTERNATIVE SPLICING / POSTSYNAPTIC CELL MEMBRANE / IONIC CHANNEL / CELL MEMBRANE / ION TRANSPORT / TRANSMEMBRANE / PHOSPHOPROTEIN / LIGAND-BINDING CORE |