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Structure paper

TitleInsights Into the Catalytic Mechanism of Tyrosine Phenol-Lyase from X-Ray Structures of Quinonoid Intermediates.
Journal, issue, pagesJ. Biol. Chem., Vol. 283, Page 29206-, Year 2008
Publish dateJan 14, 2008 (structure data deposition date)
AuthorsMilic, D. / Demidkina, T.V. / Faleev, N.G. / Matkovic-Calogovic, D. / Antson, A.A.
External linksJ. Biol. Chem. / PubMed:18715865
MethodsX-ray diffraction
Resolution1.89 - 1.95 Å
Structure data

PDB-2vlf:
Quinonoid intermediate of Citrobacter freundii tyrosine phenol-lyase formed with alanine
Method: X-RAY DIFFRACTION / Resolution: 1.89 Å

PDB-2vlh:
Quinonoid intermediate of Citrobacter freundii tyrosine phenol-lyase formed with methionine
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-PLI:
(2E)-2-{[(Z)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4(1H)-YLIDENE}METHYL]IMINO}PROPANOIC ACID

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-K:
Unknown entry

ChemComp-P33:
3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL / precipitant*YM

ChemComp-HOH:
WATER

ChemComp-PM9:
(2E)-2-{[(Z)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4(1H)-YLIDENE}METHYL]IMINO}-4-(METHYLSULFANYL)BUTANOIC ACID

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE

Source
  • citrobacter freundii (bacteria)
KeywordsLYASE / PLP-DEPENDENT ENZYME / TYROSINE DEGRADATION / QUINONOID INTERMEDIATE / PYRIDOXAL PHOSPHATE

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