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-Structure paper
Title | Structures of human monoamine oxidase B complexes with selective noncovalent inhibitors: safinamide and coumarin analogs. |
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Journal, issue, pages | J. Med. Chem., Vol. 50, Page 5848-5852, Year 2007 |
Publish date | Jul 12, 2007 (structure data deposition date) |
Authors | Binda, C. / Wang, J. / Pisani, L. / Caccia, C. / Carotti, A. / Salvati, P. / Edmondson, D.E. / Mattevi, A. |
External links | J. Med. Chem. / PubMed:17915852 |
Methods | X-ray diffraction |
Resolution | 1.6 - 2 Å |
Structure data | PDB-2v5z: PDB-2v60: PDB-2v61: |
Chemicals | ChemComp-FAD: ChemComp-SAG: ChemComp-HOH: ChemComp-C17: ChemComp-C18: |
Source |
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Keywords | OXIDOREDUCTASE / FAD / MEMBRANE / SAFINAMIDE / FLAVOPROTEIN / HUMAN MAO B STRUCTURE / REVERSIBLE INHIBITOR BINDING / MITOCHONDRION / TRANSMEMBRANE / NEUROPROTECTION / PARKINSON'S DISEASE |