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-Structure paper
Title | A transforming mutation in the pleckstrin homology domain of AKT1 in cancer. |
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Journal, issue, pages | Nature, Vol. 448, Page 439-444, Year 2007 |
Publish date | May 1, 2007 (structure data deposition date) |
Authors | Carpten, J.D. / Faber, A.L. / Horn, C. / Donoho, G.P. / Briggs, S.L. / Robbins, C.M. / Hostetter, G. / Boguslawski, S. / Moses, T.Y. / Savage, S. ...Carpten, J.D. / Faber, A.L. / Horn, C. / Donoho, G.P. / Briggs, S.L. / Robbins, C.M. / Hostetter, G. / Boguslawski, S. / Moses, T.Y. / Savage, S. / Uhlik, M. / Lin, A. / Du, J. / Qian, Y.W. / Zeckner, D.J. / Tucker-Kellogg, G. / Touchman, J. / Patel, K. / Mousses, S. / Bittner, M. / Schevitz, R. / Lai, M.H. / Blanchard, K.L. / Thomas, J.E. |
External links | Nature / PubMed:17611497 |
Methods | X-ray diffraction |
Resolution | 1.94 - 2.46 Å |
Structure data | PDB-2uzr: PDB-2uzs: |
Chemicals | ChemComp-HOH: ChemComp-4IP: |
Source |
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Keywords | TRANSFERASE / GLYCOGEN BIOSYNTHESIS / TRANSLATION REGULATION / NUCLEOTIDE- BINDING / GLYCOGEN METABOLISM / ATP-BINDING / SUGAR TRANSPORT / NUCLEAR PROTEIN / SERINE/THREONINE-PROTEIN KINASE / TRANSPORT / CARBOHYDRATE METABOLISM / KINASE / APOPTOSIS / PHOSPHORYLATION / GLUCOSE METABOLISM |