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Structure paper

TitleStructure of glycerol-3-phosphate dehydrogenase, an essential monotopic membrane enzyme involved in respiration and metabolism.
Journal, issue, pagesProc. Natl. Acad. Sci. Usa, Vol. 105, Page 3280-3285, Year 2008
Publish dateJun 19, 2007 (structure data deposition date)
AuthorsYeh, J.I. / Chinte, U. / Du, S.
External linksProc. Natl. Acad. Sci. Usa / PubMed:18296637
MethodsX-ray diffraction
Resolution1.75 - 2.3 Å
Structure data

PDB-2qcu:
Crystal structure of Glycerol-3-phosphate Dehydrogenase from Escherichia coli
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

PDB-2r45:
Crystal structure of Escherichia coli Glycerol-3-phosphate Dehydrogenase in complex with 2-phospho-d-glyceric acid
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-2r46:
Crystal structure of Escherichia coli Glycerol-3-phosphate Dehydrogenase in complex with 2-phosphopyruvic acid.
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-2r4e:
Crystal structure of Escherichia coli Glycerol-3-phosphate Dehydrogenase in complex with DHAP
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-2r4j:
Crystal structure of Escherichia coli SeMet substituted Glycerol-3-phosphate Dehydrogenase in complex with DHAP
Method: X-RAY DIFFRACTION / Resolution: 1.96 Å

Chemicals

ChemComp-BOG:
octyl beta-D-glucopyranoside / detergent*YM

ChemComp-SO4:
SULFATE ION

ChemComp-PO4:
PHOSPHATE ION

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-TAM:
TRIS(HYDROXYETHYL)AMINOMETHANE / pH buffer*YM

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-IMD:
IMIDAZOLE

ChemComp-HOH:
WATER

ChemComp-T3A:
N-(TRIS(HYDROXYMETHYL)METHYL)-3-AMINOPROPANESULFONIC ACID / pH buffer*YM

ChemComp-2PG:
2-PHOSPHOGLYCERIC ACID

ChemComp-PEP:
PHOSPHOENOLPYRUVATE

ChemComp-13P:
1,3-DIHYDROXYACETONEPHOSPHATE

ChemComp-BCN:
BICINE / pH buffer*YM

Source
  • escherichia coli (E. coli)
KeywordsOXIDOREDUCTASE / Glycerol-3-phoshate dehydrogenase / GlpD / Cytoplasm / FAD / Flavoprotein / Glycerol metabolism

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