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TitlePlasticity of S2-S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysis.
Journal, issue, pagesFebs J., Vol. 274, Page 4752-4765, Year 2007
Publish dateJul 12, 2007 (structure data deposition date)
AuthorsAgniswamy, J. / Fang, B. / Weber, I.T.
External linksFebs J. / PubMed:17697120
MethodsX-ray diffraction
Resolution2.14 - 2.8 Å
Structure data

PDB-2ql5:
Crystal Structure of caspase-7 with inhibitor AC-DMQD-CHO
Method: X-RAY DIFFRACTION / Resolution: 2.34 Å

PDB-2ql7:
Crystal Structure of Caspase-7 with inhibitor AC-IEPD-CHO
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-2ql9:
Crystal Structure of Caspase-7 with inhibitor AC-DQMD-CHO
Method: X-RAY DIFFRACTION / Resolution: 2.14 Å

PDB-2qlb:
Crystal Structure of caspase-7 with inhibitor AC-ESMD-CHO
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-2qlf:
Crystal Structure of Caspase-7 with inhibitor AC-DNLD-CHO
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-2qlj:
Crystal Structure of Caspase-7 with Inhibitor AC-WEHD-CHO
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-CIT:
CITRIC ACID

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / CYSTEINE PROTEASE / APOPTOSIS / THIOL PROTEASE / ZYMOGEN / HYDROLASE-HYDROLASE INHIBITOR COMPLEX

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