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Structure paper

TitleMolecular basis of the antimutagenic activity of the house-cleaning inosine triphosphate pyrophosphatase RdgB from Escherichia coli.
Journal, issue, pagesJ. Mol. Biol., Vol. 374, Page 1091-1103, Year 2007
Publish dateOct 19, 2001 (structure data deposition date)
AuthorsSavchenko, A. / Proudfoot, M. / Skarina, T. / Singer, A. / Litvinova, O. / Sanishvili, R. / Brown, G. / Chirgadze, N. / Yakunin, A.F.
External linksJ. Mol. Biol. / PubMed:17976651
MethodsX-ray diffraction
Resolution1.5 - 2.02 Å
Structure data

PDB-1k7k:
crystal structure of RdgB- inosine triphosphate pyrophosphatase from E. coli
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-2pyu:
Structure of the E. coli inosine triphosphate pyrophosphatase RgdB in complex with IMP
Method: X-RAY DIFFRACTION / Resolution: 2.02 Å

PDB-2q16:
Structure of the E. coli inosine triphosphate pyrophosphatase RgdB in complex with ITP
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-IMP:
INOSINIC ACID

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-CA:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-ITT:
INOSINE 5'-TRIPHOSPHATE

Source
  • escherichia coli (E. coli)
KeywordsSTRUCTURAL GENOMICS / UNKNOWN FUNCTION / MAD / His-tag / large groove / disordered Se-Met / Putative ribosomal protein / PSI / Protein Structure Initiative / Midwest Center for Structural Genomics / MCSG / HYDROLASE / ITP pyrophosphatase x-ray structure enzyme mechanism product / ITP pyrophosphatase x-ray structure enzyme mechanism substrate

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