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Structure paper

TitleStructural analysis of lac repressor bound to allosteric effectors.
Journal, issue, pagesJ. Mol. Biol., Vol. 370, Page 609-619, Year 2007
Publish dateMar 26, 2007 (structure data deposition date)
AuthorsDaber, R. / Stayrook, S. / Rosenberg, A. / Lewis, M.
External linksJ. Mol. Biol. / PubMed:17543986
MethodsX-ray diffraction
Resolution2 - 3.5 Å
Structure data

PDB-2p9h:
High resolution structure of the Lactose Repressor bound to IPTG
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-2paf:
Crystal Structure of the Lactose Repressor bound to anti-inducer ONPF in induced state
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

PDB-2pe5:
Crystal Structure of the Lac Repressor bound to ONPG in repressed state
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

Chemicals

ChemComp-IPT:
1-methylethyl 1-thio-beta-D-galactopyranoside

ChemComp-HOH:
WATER

ChemComp-NPF:
2-nitrophenyl beta-D-fucopyranoside

ChemComp-145:
2-nitrophenyl beta-D-galactopyranoside

Source
  • escherichia coli (E. coli)
  • synthetic construct (others)
KeywordsTRANSCRIPTION / Lac repressor / allosteric effectors / gene regulation / TRANSCRIPTION/DNA / DNA-binding / Transcription regulation / TRANSCRIPTION-DNA COMPLEX

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