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Structure paper

TitleBinding of sulfonium-ion analogues of di-epi-swainsonine and 8-epi-lentiginosine to Drosophila Golgi alpha-mannosidase II: The role of water in inhibitor binding.
Journal, issue, pagesProteins, Vol. 71, Page 1484-1496, Year 2008
Publish dateFeb 15, 2007 (structure data deposition date)
AuthorsKumar, N.S. / Kuntz, D.A. / Wen, X. / Pinto, B.M. / Rose, D.R.
External linksProteins / PubMed:18076078
MethodsX-ray diffraction
Resolution1.19 - 1.77 Å
Structure data

PDB-2ow6:
Golgi alpha-mannosidase II complex with (1r,5s,6s,7r,8s)-1-thioniabicyclo[4.3.0]nonan-5,7,8-triol chloride
Method: X-RAY DIFFRACTION / Resolution: 1.19 Å

PDB-2ow7:
Golgi alpha-mannosidase II complex with (1R,6S,7R,8S)-1-thioniabicyclo[4.3.0]nonan-7,8-diol chloride
Method: X-RAY DIFFRACTION / Resolution: 1.77 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-PO4:
PHOSPHATE ION

ChemComp-ZN:
Unknown entry

ChemComp-NK1:
(1R,5S,6S,7R,8S)-1-THIONIABICYCLO[4.3.0]NONAN-5,7,8-TRIOL

ChemComp-MRD:
(4R)-2-METHYLPENTANE-2,4-DIOL / precipitant*YM

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

ChemComp-NK2:
(1R,6S,7R,8S)-1-THIONIABICYCLO[4.3.0]NONAN-7,8-DIOL

Source
  • drosophila melanogaster (fruit fly)
KeywordsHYDROLASE / GLYCOSYL HYDROLASE FAMILY 38

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