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TitleThe 2.0 A crystal structure of the ER{alpha} ligand-binding domain complexed with lasofoxifene
Journal, issue, pagesProtein Sci., Vol. 16, Page 897-905, Year 2007
Publish dateFeb 12, 2007 (structure data deposition date)
AuthorsVajdos, F.F. / Hoth, L.R. / Geoghegan, K.F. / Simons, S.P. / LeMotte, P.K. / Danley, D.E. / Ammirati, M.J. / Pandit, J.
External linksProtein Sci. / PubMed:17456742
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-2ouz:
Crystal Structure of Estrogen Receptor alpha-lasofoxifene complex
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-C3D:
(5R,6S)-6-PHENYL-5-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]-5,6,7,8-TETRAHYDRONAPHTHALEN-2-OL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHORMONE/GROWTH FACTOR / Nuclear receptor / SERM / estrogen / HORMONE-GROWTH FACTOR COMPLEX

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