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Structure paper

TitleStructural basis of inhibition of the human NAD+-dependent deacetylase SIRT5 by suramin.
Journal, issue, pagesStructure, Vol. 15, Page 377-389, Year 2007
Publish dateNov 21, 2006 (structure data deposition date)
AuthorsSchuetz, A. / Min, J. / Antoshenko, T. / Wang, C.L. / Allali-Hassani, A. / Dong, A. / Loppnau, P. / Vedadi, M. / Bochkarev, A. / Sternglanz, R. / Plotnikov, A.N.
External linksStructure / PubMed:17355872
MethodsX-ray diffraction
Resolution2.06 Å
Structure data

PDB-2nyr:
Crystal Structure of Human Sirtuin Homolog 5 in Complex with Suramin
Method: X-RAY DIFFRACTION / Resolution: 2.06 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-SVR:
8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON / medication*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / HISTONE DEACETYLASE / STRUCTURAL GENOMICS / STRUCTURAL GENOMICS CONSORTIUM / SGC

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