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TitleStructure of the mitochondrial translocator protein in complex with a diagnostic ligand.
Journal, issue, pagesScience, Vol. 343, Page 1363-1366, Year 2014
Publish dateNov 11, 2013 (structure data deposition date)
AuthorsJaremko, L. / Jaremko, M. / Giller, K. / Becker, S. / Zweckstetter, M.
External linksScience / PubMed:24653034
MethodsNMR (solution)
Structure data

PDB-2mgy:
Solution structure of the mitochondrial translocator protein (TSPO) in complex with its high-affinity ligand PK11195
Method: SOLUTION NMR

Chemicals

ChemComp-PKA:
N-[(2R)-butan-2-yl]-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide

Source
  • mus musculus (house mouse)
KeywordsMEMBRANE PROTEIN / translocator protein (TSPO) / protein-ligand complex / mitochondrial membrane / PK11195 / DPC micelles / peripheral benzodiazepine receptor / helical membrane channel protein

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