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TitleThe acidic transcription activator Gcn4 binds the mediator subunit Gal11/Med15 using a simple protein interface forming a fuzzy complex.
Journal, issue, pagesMol. Cell, Vol. 44, Page 942-953, Year 2011
Publish dateFeb 7, 2012 (structure data deposition date)
AuthorsBrzovic, P.S. / Heikaus, C.C. / Kisselev, L. / Vernon, R. / Herbig, E. / Pacheco, D. / Warfield, L. / Littlefield, P. / Baker, D. / Klevit, R.E. / Hahn, S.
External linksMol. Cell / PubMed:22195967
MethodsNMR (solution)
Structure data

PDB-2lpb:
Structure of the complex of the central activation domain of Gcn4 bound to the mediator co-activator domain 1 of Gal11/med15
Method: SOLUTION NMR

Source
  • saccharomyces cerevisiae (brewer's yeast)
KeywordsTRANSCRIPTION / Mediator / Activator / Co-Activator / Nucleus / Phosphoprotein / Transcription regulation / amino acid biosynthesis / DNA-binding

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