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Structure paper

TitleStructural and Functional Consequences of an Amide-to-Ester Substitution in the Selectivity Filter of a Potassium Channel.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 128, Page 11591-11599, Year 2006
Publish dateJun 7, 2006 (structure data deposition date)
AuthorsValiyaveetil, F.I. / Sekedat, M. / Mackinnon, R. / Muir, T.W.
External linksJ. Am. Chem. Soc. / PubMed:16939283
MethodsX-ray diffraction
Resolution2.25 - 2.75 Å
Structure data

PDB-2h8p:
Structure of a K channel with an amide to ester substitution in the selectivity filter
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-2hfe:
Rb+ complex of a K channel with an amide to ester substitution in the selectivity filter
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-2hg5:
Cs+ complex of a K channel with an amide to ester substitution in the selectivity filter
Method: X-RAY DIFFRACTION / Resolution: 2.75 Å

Chemicals

ChemComp-K:
Unknown entry

ChemComp-B3H:
(2S)-2-(BUTYRYLOXY)-3-HYDROXYPROPYL NONANOATE

ChemComp-HOH:
WATER

ChemComp-RB:
RUBIDIUM ION

ChemComp-CS:
Unknown entry

Source
  • mus musculus (house mouse)
  • synthetic construct (others)
KeywordsMEMBRANE PROTEIN / Channel / Semi-synthetic / Ester

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