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-Structure paper
Title | Crystal Structures of Mouse 17alpha-Hydroxysteroid Dehydrogenase (Apoenzyme and Enzyme-NADP(H) Binary Complex): Identification of Molecular Determinants Responsible for the Unique 17alpha-reductive Activity of this Enzyme. |
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Journal, issue, pages | J. Mol. Biol., Vol. 364, Page 747-763, Year 2006 |
Publish date | Jun 20, 2006 (structure data deposition date) |
Authors | Faucher, F. / Pereira de Jesus-Tran, K. / Cantin, L. / Luu-The, V. / Labrie, F. / Breton, R. |
External links | J. Mol. Biol. / PubMed:17034817 |
Methods | X-ray diffraction |
Resolution | 1.35 - 2.9 Å |
Structure data | PDB-2hdj: PDB-2he5: PDB-2he8: PDB-2hej: |
Chemicals | ChemComp-SO4: ChemComp-NDP: ChemComp-EDO: ChemComp-HOH: ChemComp-ACT: ChemComp-BME: ChemComp-GOL: ChemComp-MPD: |
Source |
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Keywords | OXIDOREDUCTASE / HUMAN 3ALPHAHDS3 / ALDO-KETO REDUCTASE / NADPH / AKR / AKR1C2 / 17a-HSD / AKR1C21 / HSD / hydroxysteroid dehydrogenase / open conformation / apo-form / closed conformation |