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Structure paper

TitleCrystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis.
Journal, issue, pagesNature, Vol. 440, Page 368-371, Year 2006
Publish dateDec 12, 2005 (structure data deposition date)
AuthorsBlasiak, L.C. / Vaillancourt, F.H. / Walsh, C.T. / Drennan, C.L.
External linksNature / PubMed:16541079
MethodsX-ray diffraction
Resolution1.6 - 1.8 Å
Structure data

PDB-2fct:
SyrB2 with Fe(II), chloride, and alpha-ketoglutarate
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-2fcu:
SyrB2 with alpha-ketoglutarate
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-2fcv:
SyrB2 with Fe(II), bromide, and alpha-ketoglutarate
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-FE2:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-DSU:
((2R,3S,4S,5S)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)-5-((2R,3S,4S,5S,6R)-3,4,5-TRIHYDROXY-6-METHOXY-TETRAHYDRO-2H-PYRAN-2-YLOXY)-TETRAHYDROFURAN-2-YL)METHYL NONANOATE

ChemComp-AKG:
2-OXOGLUTARIC ACID

ChemComp-HOH:
WATER

ChemComp-BR:
BROMIDE ION

Source
  • pseudomonas syringae pv. syringae (bacteria)
  • pseudomonas syringae (bacteria)
KeywordsBIOSYNTHETIC PROTEIN / mononuclear iron / cupin / halogenase

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