Title Structural Basis of the Drug-Binding Specificity of Human Serum Albumin. Journal, issue, pages J. Mol. Biol. , Vol. 353, Page 38-, Year 2005Publish date Jul 25, 2005 (structure data deposition date) AuthorsGhuman, J. / Zunszain, P.A. / Petitpas, I. / Bhattacharya, A.A. / Otagiri, M. / Curry, S. External links J. Mol. Biol. / PubMed:16169013Methods X-ray diffraction Resolution 2.25 - 3.2 Å Structure data PDB-2bx8 : Structure viewer Human serum albumin complexed with azapropazone Method : X-RAY DIFFRACTION / Resolution : 2.7 Å
PDB-2bxa : Structure viewer Human serum albumin complexed with 3-carboxy-4-methyl-5-propyl-2- furanpropanoic acid (CMPF) Method : X-RAY DIFFRACTION / Resolution : 2.35 Å
PDB-2bxb : Structure viewer Human serum albumin complexed with oxyphenbutazone Method : X-RAY DIFFRACTION / Resolution : 3.2 Å
PDB-2bxc : Structure viewer Human serum albumin complexed with phenylbutazone Method : X-RAY DIFFRACTION / Resolution : 3.1 Å
PDB-2bxd : Structure viewer Human serum albumin complexed with warfarin Method : X-RAY DIFFRACTION / Resolution : 3.05 Å
PDB-2bxe : Structure viewer Human serum albumin complexed with diflunisal Method : X-RAY DIFFRACTION / Resolution : 2.95 Å
PDB-2bxf : Structure viewer Human serum albumin complexed with diazepam Method : X-RAY DIFFRACTION / Resolution : 2.95 Å
PDB-2bxg : Structure viewer Human serum albumin complexed with ibuprofen Method : X-RAY DIFFRACTION / Resolution : 2.7 Å
PDB-2bxh : Structure viewer Human serum albumin complexed with indoxyl sulfate Method : X-RAY DIFFRACTION / Resolution : 2.25 Å
PDB-2bxi : Structure viewer Human serum albumin complexed with myristate and azapropazone Method : X-RAY DIFFRACTION / Resolution : 2.5 Å
PDB-2bxk : Structure viewer Human serum albumin complexed with myristate, azapropazone and indomethacinMethod : X-RAY DIFFRACTION / Resolution : 2.4 Å
PDB-2bxl : Structure viewer Human serum albumin complexed with myristate and 3,5-diiodosalicylic acid Method : X-RAY DIFFRACTION / Resolution : 2.6 Å
PDB-2bxm : Structure viewer Human serum albumin complexed with myristate and indomethacin Method : X-RAY DIFFRACTION / Resolution : 2.5 Å
PDB-2bxn : Structure viewer Human serum albumin complexed with myristate and iodipamide Method : X-RAY DIFFRACTION / Resolution : 2.65 Å
PDB-2bxo : Structure viewer Human serum albumin complexed with myristate and oxyphenbutazone Method : X-RAY DIFFRACTION / Resolution : 2.6 Å
PDB-2bxp : Structure viewer Human serum albumin complexed with myristate and phenylbutazone Method : X-RAY DIFFRACTION / Resolution : 2.3 Å
PDB-2bxq : Structure viewer Human serum albumin complexed with myristate, phenylbutazone and indomethacinMethod : X-RAY DIFFRACTION / Resolution : 2.6 Å
Chemicals ChemComp-AZQ : Structure viewer AZAPROPAZONE / antiinflammatory*YM / Azapropazone
ChemComp-C1F : Structure viewer 3-CARBOXY-4-METHYL-5-PROPYL-2-FURANPROPIONIC
ChemComp-OPB : Structure viewer 4-BUTYL-1-(4-HYDROXYPHENYL)-2-PHENYLPYRAZOLIDINE-3,5-DIONE / antiinflammatory*YM / Oxyphenbutazone
ChemComp-P1Z : Structure viewer 4-BUTYL-1,2-DIPHENYL-PYRAZOLIDINE-3,5-DIONE / antiinflammatory*YM / Phenylbutazone
ChemComp-1FL : Structure viewer 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID / antiinflammatory*YM / Diflunisal
ChemComp-DZP : Structure viewer 7-CHLORO-1-METHYL-5-PHENYL-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE / Diazepam
ChemComp-IBP : Structure viewer IBUPROFEN / antiinflammatory, medication*YM / Dexibuprofen
ChemComp-IOS : Structure viewer 3-SULFOOXY-1H-INDOLE / toxin*YM / Indoxyl sulfate
ChemComp-IMN : Structure viewer INDOMETHACIN / medication, antiinflammatory*YM / Indometacin
ChemComp-DIU : Structure viewer 2-HYDROXY-3,5-DIIODO-BENZOIC ACID
ChemComp-IDB : Structure viewer 3-[5-[(3-CARBOXY-2,4,6-TRIIODO-PHENYL)CARBAMOYL]PENTANOYLAMINO]-2,4,6-TRIIODO-BENZOIC ACID / Adipiodone
Source homo sapiens (human) Keywords TRANSPORT PROTEIN / ALBUMIN / CARRIER PROTEIN / LIPID-BINDING / FATTY ACID / METAL- BINDING / DRUG-BINDING / AZAPROPAZONE / TRANSPORT / METAL-BINDING / 3-CARBOXY-4-METHYL-5-PROPYL-2- FURANPROPANOIC ACID (CMPF) / OXYPHENBUTAZONE / PHENYLBUTAZONE / WARFARIN / DIAZEPAM / IBUPROFEN / INDOXYL SULFATE / MYRISTATE / INDOMETHACIN / 3 / 5-DIIODOSALICYLIC ACID / IODIPAMIDE / DRUG- BINDING