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TitleInteraction of Benzoate Pyrimidine Analogues with Class 1A Dihydroorotate Dehydrogenase from Lactococcus Lactis.
Journal, issue, pagesBiochemistry, Vol. 46, Page 5741-, Year 2007
Publish dateMay 23, 2005 (structure data deposition date)
AuthorsWolfe, A.E. / Thymark, M. / Gattis, S.G. / Fagan, R.L. / Hu, Y.-C. / Johansson, E. / Arent, S. / Larsen, S. / Palfey, B.A.
External linksBiochemistry / PubMed:17444658
MethodsX-ray diffraction
Resolution2.04 - 2.3 Å
Structure data

PDB-2bsl:
Crystal structure of L. lactis dihydroorotate dehydrogense A in complex with 3,4-dihydroxybenzoate
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-2bx7:
Crystal structure of L. lactis dihydroorotate dehydrogense A in complex with 3,5-dihydroxybenzoate
Method: X-RAY DIFFRACTION / Resolution: 2.04 Å

Chemicals

ChemComp-FMN:
FLAVIN MONONUCLEOTIDE

ChemComp-ACT:
ACETATE ION

ChemComp-MG:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-DHB:
3,4-DIHYDROXYBENZOIC ACID

ChemComp-HOH:
WATER

ChemComp-34D:
3,5-DIHYDROXYBENZOATE

Source
  • lactococcus lactis (lactic acid bacteria)
KeywordsOXIDOREDUCTASE / NUCLEOTIDE METABOLISM / DIHYDROOROTATE DEHYDROGENASE / FMN / FLAVOPROTEIN / PYRIMIDINE BIOSYNTHESIS

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