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Structure paper

TitleThe structure of glycogen phosphorylase b with an alkyldihydropyridine-dicarboxylic acid compound, a novel and potent inhibitor.
Journal, issue, pagesStructure, Vol. 5, Page 1413-1425, Year 1997
Publish dateOct 13, 1998 (structure data deposition date)
AuthorsZographos, S.E. / Oikonomakos, N.G. / Tsitsanou, K.E. / Leonidas, D.D. / Chrysina, E.D. / Skamnaki, V.T. / Bischoff, H. / Goldmann, S. / Watson, K.A. / Johnson, L.N.
External linksStructure / PubMed:9384557
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-2amv:
THE STRUCTURE OF GLYCOGEN PHOSPHORYLASE B WITH AN ALKYL-DIHYDROPYRIDINE-DICARBOXYLIC ACID
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE

ChemComp-BIN:
2,3-DICARBOXY-4-(2-CHLORO-PHENYL)-1-ETHYL-5-ISOPROPOXYCARBONYL-6-METHYL-PYRIDINIUM

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • oryctolagus cuniculus (rabbit)
KeywordsTRANSFERASE / GLYCOGEN PHOSPHORYLASE / GLYCOGEN METABOLISM / DIABETES / INHIBITORS / GLYCOSYLTRANSFERASE

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