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Structure paper

TitleStructures of adamalysin II with peptidic inhibitors. Implications for the design of tumor necrosis factor alpha convertase inhibitors.
Journal, issue, pagesProtein Sci., Vol. 7, Page 283-292, Year 1998
Publish dateOct 12, 1997 (structure data deposition date)
AuthorsGomis-Ruth, F.X. / Meyer, E.F. / Kress, L.F. / Politi, V.
External linksPubMed:9521103
MethodsX-ray diffraction
Resolution2.6 - 2.8 Å
Structure data

PDB-2aig:
ADAMALYSIN II WITH PEPTIDOMIMETIC INHIBITOR POL647
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-3aig:
ADAMALYSIN II WITH PEPTIDOMIMETIC INHIBITOR POL656
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-0GR:
N-(furan-2-ylcarbonyl)-L-leucyl-L-tryptophan

ChemComp-ZN:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-0ZC:
(3R)-2-[N-(furan-2-ylcarbonyl)-L-leucyl]-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid

Source
  • crotalus adamanteus (eastern diamondback rattlesnake)
KeywordsHYDROLAST/HYDROLASE INHIBITOR / ZINC PROTEASE / METALLOENDOPETIDASE / COMPLEX OF METALLOPROTEASE-INHIBITOR / HYDROLAST-HYDROLASE INHIBITOR COMPLEX / HYDROLASE/HYDROLASE INHIBITOR / SNAKE VENOM METALLOENDOPETIDASE / METALLOPROTEASE / HYDROLASE-HYDROLASE INHIBITOR COMPLEX

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