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TitleStructure of tropinone reductase-II complexed with NADP+ and pseudotropine at 1.9 A resolution: implication for stereospecific substrate binding and catalysis.
Journal, issue, pagesBiochemistry, Vol. 38, Page 7630-7637, Year 1999
Publish dateJan 26, 1999 (structure data deposition date)
AuthorsYamashita, A. / Kato, H. / Wakatsuki, S. / Tomizaki, T. / Nakatsu, T. / Nakajima, K. / Hashimoto, T. / Yamada, Y. / Oda, J.
External linksBiochemistry / PubMed:10387002
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-2ae2:
TROPINONE REDUCTASE-II COMPLEXED WITH NADP+ AND PSEUDOTROPINE
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-NAP:
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-PTO:
PSEUDOTROPINE / alkaloid*YM

ChemComp-HOH:
WATER

Source
  • datura stramonium (jimsonweed)
KeywordsOXIDOREDUCTASE / TROPANE ALKALOID BIOSYNTHESIS / REDUCTION OF TROPINONE TO PSEUDOTROPINE / SHORT-CHAIN DEHYDROGENASE

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