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Structure paper

TitleIsohelicity and phasing in drug--DNA sequence recognition: crystal structure of a tris(benzimidazole)--oligonucleotide complex.
Journal, issue, pagesBiochemistry, Vol. 35, Page 13745-13752, Year 1996
Publish dateSep 27, 1996 (structure data deposition date)
AuthorsClark, G.R. / Gray, E.J. / Neidle, S. / Li, Y.H. / Leupin, W.
External linksBiochemistry / PubMed:8901516
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-263d:
ISOHELICITY AND PHASING IN DRUG-DNA SEQUENCE RECOGNITION: CRYSTAL STRUCTURE OF A TRIS(BENZIMIDAZOLE)-OLIGONUCLEOTIDE COMPLEX
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-TBZ:
2''-(4-METHOXYPHENYL)-5-(3-AMINO-1-PYRROLIDINYL)-2,5',2',5''-TRI-BENZIMIDAZOLE

ChemComp-HOH:
WATER

KeywordsDNA / B-DNA / DOUBLE HELIX / COMPLEXED WITH DRUG

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