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Structure paper

TitleStructural mechanism for sterol sensing and transport by OSBP-related proteins
Journal, issue, pagesNature, Vol. 437, Page 154-158, Year 2005
Publish dateApr 26, 2005 (structure data deposition date)
AuthorsIm, Y.J. / Raychaudhuri, S. / Prinz, W.A. / Hurley, J.H.
External linksNature / PubMed:16136145
MethodsX-ray diffraction
Resolution1.5 - 2.5 Å
Structure data

PDB-1zht:
Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-1zhw:
Structure of yeast oxysterol binding protein Osh4 in complex with 20-hydroxycholesterol
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-1zhx:
Structure of yeast oxysterol binding protein Osh4 in complex with 25-hydroxycholesterol
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-1zhy:
Structure of yeast oxysterol binding protein Osh4 in complex with cholesterol
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-1zhz:
Structure of yeast oxysterol binding protein Osh4 in complex with ergosterol
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-1zi7:
Structure of truncated yeast oxysterol binding protein Osh4
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-HCR:
7-HYDROXYCHOLESTEROL

ChemComp-HOH:
WATER

ChemComp-PB:
LEAD (II) ION

ChemComp-HC2:
20-HYDROXYCHOLESTEROL

ChemComp-HC3:
25-HYDROXYCHOLESTEROL

ChemComp-CLR:
CHOLESTEROL

ChemComp-ERG:
ERGOSTEROL

ChemComp-SO4:
SULFATE ION

Source
  • saccharomyces cerevisiae (brewer's yeast)
KeywordsLIPID BINDING PROTEIN / Oxysterol sterol binding protein cholesterol / oxysterol / sterol binding protein

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