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-Structure paper
Title | Structural locations and functional roles of new subsites S5, S6, and S7 in memapsin 2 (beta-secretase). |
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Journal, issue, pages | Biochemistry, Vol. 44, Page 105-112, Year 2005 |
Publish date | Oct 4, 2004 (structure data deposition date) |
Authors | Turner III, R.T. / Hong, L. / Koelsch, G. / Ghosh, A.K. / Tang, J. |
External links | Biochemistry / PubMed:15628850 |
Methods | X-ray diffraction |
Resolution | 1.9 - 2 Å |
Structure data | PDB-1xn2: PDB-1xn3: |
Chemicals | ChemComp-HOH: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / beta secretase / memapsin2 / BACE / ASP2 / Aspartic protease / Alzheimer's disease / Drug design / HYDROLASE-HYDROLASE INHIBITOR complex |