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-Structure paper
Title | A Mechanism for the Potent Inhibition of Eukaryotic Acetyl-Coenzyme a Carboxylase by Soraphen A, a Macrocyclic Polyketide Natural Product |
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Journal, issue, pages | Mol. Cell, Vol. 16, Page 881-, Year 2004 |
Publish date | Oct 5, 2004 (structure data deposition date) |
![]() | Shen, Y. / Volrath, S.L. / Weatherly, S.C. / Elich, T.D. / Tong, L. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.8 - 2.5 Å |
Structure data | ![]() PDB-1w93: ![]() PDB-1w96: |
Chemicals | ![]() ChemComp-HOH: ![]() ChemComp-S1A: |
Source |
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![]() | LIGASE / OBESITY / DIABETES / FATTY ACID METABOLISM / STRUCTURE-BASED DRUG DESIGN / ALLOSTERIC INHIBITION / POLYKETIDE |