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-Structure paper
Title | Inhibition of Leishmania Major Pteridine Reductase by 2,4,6-Triaminoquinazoline: Structure of the Nadph Ternary Complex |
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Journal, issue, pages | Acta Crystallogr. ,Sect. D, Vol. 60, Page 1780-, Year 2004 |
Publish date | Jun 2, 2004 (structure data deposition date) |
Authors | Mcluskey, K. / Gibellini, F. / Carvalho, P. / Avery, M. / Hunter, W. |
External links | Acta Crystallogr. ,Sect. D / PubMed:15388924 |
Methods | X-ray diffraction |
Resolution | 2.6 Å |
Structure data | PDB-1w0c: |
Chemicals | ChemComp-NAP: ChemComp-TAQ: ChemComp-HOH: |
Source |
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Keywords | OXIDOREDUCTASE / ENZYME INHIBITOR / PTERIN / SHORT-CHAIN REDUCTASE / LEISHMANIA / METHOTREXATE / TRYPANOSOMA / NADP / METHOTREXATE RESISTANCE |