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Structure paper

TitleNicotine and Carbamylcholine Binding to Nicotinic Acetylcholine Receptors as Studied in Achbp Crystal Structures
Journal, issue, pagesNeuron, Vol. 41, Page 907-, Year 2004
Publish dateJan 15, 2004 (structure data deposition date)
AuthorsCelie, P.H.N. / Van Rossum-Fikkert, S.E. / Van Dijk, W.J. / Brejc, K. / Smit, A.B. / Sixma, T.K.
External linksNeuron / PubMed:15046723
MethodsX-ray diffraction
Resolution2.2 - 2.5 Å
Structure data

PDB-1uv6:
X-ray structure of acetylcholine binding protein (AChBP) in complex with carbamylcholine
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-1uw6:
X-ray structure of acetylcholine binding protein (AChBP) in complex with nicotine
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-1ux2:
X-ray structure of acetylcholine binding protein (AChBP)
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-CCE:
2-[(AMINOCARBONYL)OXY]-N,N,N-TRIMETHYLETHANAMINIUM

ChemComp-HOH:
WATER

ChemComp-NCT:
(S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE / alkaloid*YM

ChemComp-EPE:
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH buffer*YM

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-SO4:
SULFATE ION

ChemComp-NH4:
AMMONIUM ION

Source
  • lymnaea stagnalis (great pond snail)
KeywordsGLYCOPROTEIN / IMMUNOGLOBULIN DOMAIN / PENTAMER / IGG FOLD / ACETYLCHOLINE / NICOTINE

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