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TitleInhibition of a mitotic motor protein: where, how, and conformational consequences
Journal, issue, pagesJ. Mol. Biol., Vol. 335, Page 547-554, Year 2004
Publish dateJul 15, 2003 (structure data deposition date)
AuthorsYan, Y. / Sardana, V. / Xu, B. / Homnick, C. / Halczenko, W. / Buser, C.A. / Schaber, M. / Hartman, G.D. / Huber, H.E. / Kuo, L.C.
External linksJ. Mol. Biol. / PubMed:14672662
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-1q0b:
Crystal structure of the motor protein KSP in complex with ADP and monastrol
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-NAT:
ETHYL 4-(3-HYDROXYPHENYL)-6-METHYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE / inhibitor*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCELL CYCLE / motor protein / monastrol

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