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Structure paper

TitleThe three-dimensional structure of apopain/CPP32, a key mediator of apoptosis.
Journal, issue, pagesNat. Struct. Biol., Vol. 3, Page 619-625, Year 1996
Publish dateJun 6, 1996 (structure data deposition date)
AuthorsRotonda, J. / Nicholson, D.W. / Fazil, K.M. / Gallant, M. / Gareau, Y. / Labelle, M. / Peterson, E.P. / Rasper, D.M. / Ruel, R. / Vaillancourt, J.P. ...Rotonda, J. / Nicholson, D.W. / Fazil, K.M. / Gallant, M. / Gareau, Y. / Labelle, M. / Peterson, E.P. / Rasper, D.M. / Ruel, R. / Vaillancourt, J.P. / Thornberry, N.A. / Becker, J.W.
External linksNat. Struct. Biol. / PubMed:8673606
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-1pau:
Crystal structure of the complex of apopain with the tetrapeptide aldehyde inhibitor AC-DEVD-CHO
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / CYSTEINE PROTEASE / CASPASE-3 / APOPAIN / CPP32 / YAMA / PROTEASE-INHIBITOR COMPLEX / HYDROLASE-HYDROLASE INHIBITOR COMPLEX

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