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Structure paper

TitleCrystal Structure of Human Cytochrome P450 2C9 with Bound Warfarin
Journal, issue, pagesNature, Vol. 424, Page 464-, Year 2003
Publish dateApr 23, 2003 (structure data deposition date)
AuthorsWilliams, P.A. / Cosme, J. / Ward, A. / Angove, H.C. / Matak Vinkovic, D. / Jhoti, H.
External linksNature / PubMed:12861225
MethodsX-ray diffraction
Resolution2.55 - 2.6 Å
Structure data

PDB-1og2:
Structure of human cytochrome P450 CYP2C9
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-1og5:
Structure of human cytochrome P450 CYP2C9
Method: X-RAY DIFFRACTION / Resolution: 2.55 Å

Chemicals

ChemComp-HEC:
HEME C

ChemComp-HOH:
WATER

ChemComp-SWF:
S-WARFARIN / medication, anticoagulant*YM

Source
  • homo sapiens (human)
KeywordsELECTRON TRANSPORT / DRUG METABOLISM / OXIDOREDUCTASE / HEME / MONOOXYGENASE

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