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Structure paper

TitleCrystal Structures of RIalpha Subunit of Cyclic Adenosine 5'-Monophosphate (cAMP)-Dependent Protein Kinase Complexed with (R(p))-Adenosine 3',5'-Cyclic Monophosphothioate and (S(p))-Adenosine 3',5'-Cyclic Monophosphothioate, the Phosphothioate Analogues of cAMP.
Journal, issue, pagesBiochemistry, Vol. 43, Page 6620-6629, Year 2004
Publish dateDec 10, 2002 (structure data deposition date)
AuthorsWu, J. / Jones, J.M. / Xuong, N.H. / Eyck, L.F. / Taylor, S.S.
External linksBiochemistry / PubMed:15157095
MethodsX-ray diffraction
Resolution2.3 - 2.4 Å
Structure data

PDB-1ne4:
Crystal Structure of Rp-cAMP Binding R1a Subunit of cAMP-dependent Protein Kinase
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-1ne6:
Crystal structure of Sp-cAMP binding R1a subunit of cAMP-dependent protein kinase
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-RP1:
6-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL

ChemComp-HOH:
WATER

ChemComp-SP1:
6-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL

Source
  • bos taurus (domestic cattle)
KeywordsHYDROLASE / cAMP-dependent protein kinase / R1a subunit / cAMP analog / Rp-cAMP / Sp-cAMP

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