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Structure paper

TitleDiscovery and characterization of cooperative ligand binding in the adaptive region of interleukin-2
Journal, issue, pagesBiochemistry, Vol. 42, Page 6475-6483, Year 2003
Publish dateDec 3, 2002 (structure data deposition date)
AuthorsHyde, J. / Braisted, A.C. / Randal, M. / Arkin, M.R.
External linksBiochemistry / PubMed:12767230
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-1nbp:
Crystal Structure Of Human Interleukin-2 Y31C Covalently Modified At C31 With 3-Mercapto-1-(1,3,4,9-tetrahydro-B-carbolin-2-yl)-propan-1-one
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-MHC:
3-MERCAPTO-1-(1,3,4,9-TETRAHYDRO-B-CARBOLIN-2-YL)-PROPAN-1-ONE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCYTOKINE / FOUR-HELIX BUNDLE / SMALL MOLECULE COMPLEX

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