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Title | Enzymatic and structural analysis of inhibitors designed against Mycobacterium tuberculosis thymidylate kinase. New insights into the phosphoryl transfer mechanism. |
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Journal, issue, pages | J. Biol. Chem., Vol. 278, Page 4963-4971, Year 2003 |
Publish date | Sep 18, 2002 (structure data deposition date) |
![]() | Haouz, A. / Vanheusden, V. / Munier-Lehmann, H. / Froeyen, M. / Herdewijn, P. / Van Calenbergh, S. / Delarue, M. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2 - 2.45 Å |
Structure data | ![]() PDB-1mrn: ![]() PDB-1mrs: |
Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-MG: ![]() ChemComp-T5A: ![]() ChemComp-HOH: ![]() ChemComp-5HU: |
Source |
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![]() | TRANSFERASE / TRANSFERASE (ATP:TMP PHOSPHOTRANSFERASE) / KINASE |