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Structure paper

TitleStructural basis for the inhibition of the biosynthesis of biotin by the antibiotic amiclenomycin
Journal, issue, pagesJ. Biol. Chem., Vol. 277, Page 43352-43358, Year 2002
Publish dateSep 2, 2002 (structure data deposition date)
AuthorsSandmark, J. / Mann, S. / Marquet, A. / Schneider, G.
External linksJ. Biol. Chem. / PubMed:12218056
MethodsX-ray diffraction
Resolution1.81 - 2.15 Å
Structure data

PDB-1mly:
Crystal Structure of 7,8-Diaminopelargonic Acid Synthase in complex with the cis isomer of amiclenomycin
Method: X-RAY DIFFRACTION / Resolution: 1.81 Å

PDB-1mlz:
Crystal Structure of 7,8-Diaminopelargonic Acid Synthase in complex with the trans-isomer of amiclenomycin.
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

Chemicals

ChemComp-ACZ:
CIS-AMICLENOMYCIN

ChemComp-NA:
Unknown entry

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE

ChemComp-HOH:
WATER

ChemComp-TZA:
TRANS-AMICLENOMYCIN

Source
  • escherichia coli (E. coli)
KeywordsTRANSFERASE / Aminotransferase / Fold type I / subclass II / amiclenomycin

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