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Structure paper

TitleThe cystine knot promotes folding and not thermodynamic stability in vascular endothelial growth factor
Journal, issue, pagesJ. Biol. Chem., Vol. 277, Page 43410-43416, Year 2002
Publish dateAug 28, 2002 (structure data deposition date)
AuthorsMuller, Y.A. / Heiring, C. / Misselwitz, R. / Welfle, K. / Welfle, H.
External linksJ. Biol. Chem. / PubMed:12207021
MethodsX-ray diffraction
Resolution1.32 - 2.5 Å
Structure data

PDB-1mjv:
DISULFIDE DEFICIENT MUTANT OF VASCULAR ENDOTHELIAL GROWTH FACTOR A (C51A and C60A)
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-1mkg:
DISULFIDE DEFICIENT MUTANT OF VASCULAR ENDOTHELIAL GROWTH FACTOR A (C57A and C102A)
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-1mkk:
Disulfide deficient mutant of vascular endothelial growth factor A (C61A and C104A)
Method: X-RAY DIFFRACTION / Resolution: 1.32 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHORMONE/GROWTH FACTOR / cystine-knot growth factor / HORMONE-GROWTH FACTOR COMPLEX

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