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-Structure paper
Title | Tryptophan 80 and leucine 143 are critical for the hydride transfer step of thymidylate synthase by controlling active site access. |
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Journal, issue, pages | Biochemistry, Vol. 41, Page 7021-7029, Year 2002 |
Publish date | Feb 6, 2002 (structure data deposition date) |
![]() | Fritz, T.A. / Liu, L. / Finer-Moore, J.S. / Stroud, R.M. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.75 - 2.6 Å |
Structure data | ![]() PDB-1kzi: ![]() PDB-1kzj: |
Chemicals | ![]() ChemComp-CO3: ![]() ChemComp-UMP: ![]() ChemComp-THG: ![]() ChemComp-DTU: ![]() ChemComp-GOL: ![]() ChemComp-DTT: ![]() ChemComp-HOH: ![]() ChemComp-CB3: |
Source |
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![]() | TRANSFERASE / Enzyme substrate complex / Enzyme substrate cofactor analog complex |