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Structure paper

TitleThe crystal structure of spermidine synthase with a multisubstrate adduct inhibitor.
Journal, issue, pagesNat. Struct. Biol., Vol. 9, Page 27-31, Year 2002
Publish dateMay 14, 2001 (structure data deposition date)
AuthorsKorolev, S. / Ikeguchi, Y. / Skarina, T. / Beasley, S. / Arrowsmith, C. / Edwards, A. / Joachimiak, A. / Pegg, A.E. / Savchenko, A.
External linksNat. Struct. Biol. / PubMed:11731804
MethodsX-ray diffraction
Resolution1.5 - 1.8 Å
Structure data

PDB-1inl:
Crystal Structure of Spermidine Synthase from Thermotoga Maritima
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-1jq3:
Crystal Structure of Spermidine Synthase in Complex with Transition State Analogue AdoDATO
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-AAT:
S-ADENOSYL-1,8-DIAMINO-3-THIOOCTANE

Source
  • thermotoga maritima (bacteria)
KeywordsTRANSFERASE / beta-barrel / Rossmann fold / Structural Genomics / PSI / Protein Structure Initiative / Midwest Center for Structural Genomics / MCSG / aminopropyltransferase / homo-tetramer / thermophyle / transition-state analogue

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