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TitleA New, Simple, High-Affinity Glycosidase Inhibitor: Analysis of Binding through X-ray Crystallography, Mutagenesis, and Kinetic Analysis
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 122, Page 4229-4230, Year 2000
Publish dateOct 25, 2002 (structure data deposition date)
AuthorsWilliams, S.J. / Notenboom, V. / Wicki, J. / Rose, D.R. / Withers, S.G.
External linksJ. Am. Chem. Soc. / Search PubMed
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-1j01:
Crystal Structure Of The Xylanase Cex With Xylobiose-Derived Inhibitor Isofagomine lactam
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-XIL:
(3S,4R)-3-hydroxy-2-oxopiperidin-4-yl beta-D-xylopyranoside

ChemComp-HOH:
WATER

Source
  • cellulomonas fimi (bacteria)
KeywordsHYDROLASE / CEX / XYLANASE / DEOXYNOJIRIMYCIN INHIBITOR / CELLULOSE DEGRADATION

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