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Structure paper

TitleThe Lys103Asn mutation of HIV-1 RT: a novel mechanism of drug resistance.
Journal, issue, pagesJ. Mol. Biol., Vol. 309, Page 437-445, Year 2001
Publish dateDec 13, 2000 (structure data deposition date)
AuthorsHsiou, Y. / Ding, J. / Das, K. / Clark Jr., A.D. / Boyer, P.L. / Lewi, P. / Janssen, P.A. / Kleim, J.P. / Rosner, M. / Hughes, S.H. / Arnold, E.
External linksJ. Mol. Biol. / PubMed:11371163
MethodsX-ray diffraction
Resolution2.7 - 3 Å
Structure data

PDB-1hpz:
HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-1hqe:
HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-1hqu:
HUMAN IMMUNODEFICIENCY VIRUS TYPE 1
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-AAP:
ALPHA-(2,6-DICHLOROPHENYL)-ALPHA-(2-ACETYL-5-METHYLANILINO)ACETAMIDE

ChemComp-HOH:
WATER

ChemComp-HBY:
(S)-4-ISOPROPOXYCARBONYL-6-METHOXY-3-METHYLTHIOMETHYL-3,4-DIHYDROQUINOXALIN-2(1H)-THIONE

Source
  • human immunodeficiency virus 1
KeywordsTRANSFERASE / NUCLEOTIDYLTRANSFERASE

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