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-Structure paper
Title | Identification of a series of tricyclic natural products as potent broad spectrum inhibitors of metallo-beta-lactamases |
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Journal, issue, pages | Antimicrob. Agents Chemother., Vol. 46, Page 1880-1886, Year 2002 |
Publish date | Dec 1, 2000 (structure data deposition date) |
![]() | Payne, D.J. / Hueso-Rodriguez, J.A. / Boyd, H. / Concha, N.O. / Janson, C.A. / Gilpin, M. / Bateson, J.H. / Chever, C. / Niconovich, N.L. / Pearson, S. ...Payne, D.J. / Hueso-Rodriguez, J.A. / Boyd, H. / Concha, N.O. / Janson, C.A. / Gilpin, M. / Bateson, J.H. / Chever, C. / Niconovich, N.L. / Pearson, S. / Rittenhouse, S. / Tew, D. / Diez, E. / Perez, P. / de la Fuente, J. / Rees, M. / Rivera-Sagredo, A. |
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Methods | X-ray diffraction |
Resolution | 2.5 Å |
Structure data | ![]() PDB-1hlk: ![]() PDB-1kr3: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-NA: ![]() ChemComp-113: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / alpha-beta structure / beta-sandwich / beta sandwich / protein-inhibitor complex / metallo / beta-lactamase |